Recombinant Rat TIM1/HACVR1 Protein (His & Fc Tag)
Product Specifications
Background
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â … integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
Synonyms
Havcr1; KIM-1; Kim1
UniProt
O54947
Accession Number
NP_775172.1
Expression System
HEK293 Cells
Tag
C-His & N-Fc
Sequence
Ser 18-Val 238
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 93 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/k8hhr8
Product MSDS
https://789.bio/eb/fXznTS
Calculated Molecular Weight
52.6 kDa
Observed Molecular Weight
90-100 kDa
Species
Rat
Curated Selection
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