Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)
Product Specifications
Background
Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.
Abbreviation
TSLP
Synonyms
TSLP; Thymic stroma-derived lymphopoietin; Thymic stromal lymphopoietin
UniProt
A0A7N9CAT7
Accession Number
XP_005557555.1
Expression System
E.coli
Tag
C-His
Sequence
Tyr29-Gln159 (Glu37Gln)
Applications
BLI
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Loaded Anti-Human TSLP mAb-Fc on Protein A Biosensor, can bind Cynomolgus TSLP-His with an affinity constant of 0.07 nM as determined in BLI assay.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/svalco
Product MSDS
https://789.bio/eb/5a1KOC
Calculated Molecular Weight
16.2 kDa
Observed Molecular Weight
16 kDa
Species
Cynomolgus macaques
Available Sizes
Curated Selection
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