Recombinant Cynomolgus FGL1 (C-Avi-6His) Biotinylated
Product Specifications
Background
Fibrinogen-like protein 1 (FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
Abbreviation
FGL1
Synonyms
FGL1; Fibrinogen-like protein 1; HFREP-1; HP-041; Hepassocin; LFIRE-1
UniProt
A0A2K5X990
Accession Number
A0A2K5X990
Expression System
HEK293 Cells
Conjugation
Biotinylated
Tag
C-Avi-His
Sequence
Leu23-Ile312
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
34.8 kDa
Observed Molecular Weight
36 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.
Species
Cynomolgus macaques
Available Sizes
Documents
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