Recombinant Rhesus macaque IFNAR1 Protein (His Tag)
Product Specifications
Background
Interferon-alpha/beta receptor 1 (IFN-alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Abbreviation
IFNAR1
Synonyms
AVP; Alpha-type antiviral protein; CRF2-1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; I; IFN-alpha-REC; IFN-alpha/beta R1; IFN-alpha/beta receptor 1; beta-type antiviral protein; human interferon-alpha receptor (HuIFN-alpha-Rec) 10IFRC
UniProt
A0A7N9D7J0
Accession Number
XP_005548864.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala25-Lys437
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/kl5ts8
Product MSDS
https://789.bio/eb/unT88O
Calculated Molecular Weight
48.4 kDa
Observed Molecular Weight
70-120 kDa
Species
Rhesus macaque
Available Sizes
Curated Selection
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