Recombinant Cynomolgus PD-L2/B7-DC/CD273 Protein (Fc Tag)

Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

B7-DC; B7DC; Butyrophilin B7-DC; CD273; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; PDCD1L2; PDCD1LG2; PDL2; Programmed Cell Death 1 Ligand 2; Programmed Death Ligand 2

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.