Recombinant Mouse G-CSF protein (N-His)
Product Specifications
Background
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.
Abbreviation
G-CSF
Synonyms
OPGL; CD254; ODF (Osteoclast Differentiation Factor) ; TNFSF11; TRANCE (TNF-Related Activation-induced Cytokine) ; sRNAK Ligand; soluble Receptor Activator of NF-kB Ligand
UniProt
P09920
Accession Number
P09920
Expression System
E.coli
Tag
N-His
Sequence
Val 31-Ala 208
Applications
Cell culture
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
50 2 x 107 IU/mg.7
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
19.8 kDa
Observed Molecular Weight
17-25 kDa
Species
Mouse
Available Sizes
Documents
Curated Selection
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