Recombinant Mouse M-CSF protein (His Tag)
Product Specifications
Background
Macrophage colony-stimulating factor 1 (M-csf) is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Abbreviation
M-CSF
Synonyms
Ath; Ath-; Ath-1; Ath1; CD134; CD134L; OX-40L; OX4; TNFSF4; TXGP1; Tnlg2b; Txgp; Txgp1l; gp3; gp34
UniProt
P07141
Accession Number
P07141
Expression System
E.coli
Tag
C-His
Sequence
Lys32-Pro187
Applications
Cell culture
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
505 x 105 IU/mg.5
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
19.0 kDa
Observed Molecular Weight
17-25 kDa
Species
Mouse
Available Sizes
Documents
Curated Selection
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