Recombinant Mouse IL-34 protein (His Tag)
Product Specifications
Background
Interleukin-34 (IL-34) is a protein that promotes the proliferation, survival and differentiation of monocytes and macrophages. It also promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. IL-34 plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Abbreviation
IL-34
Synonyms
Za11; Il34
UniProt
Q8R1R4
Accession Number
Q8R1R4
Expression System
E.coli
Tag
C-His
Sequence
Asn 21-Pro 235
Applications
Cell culture
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
50 3.3 x 104 IU/mg.4
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
25.5 kDa
Observed Molecular Weight
25 kDa
Species
Mouse
Available Sizes
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