Recombinant Mouse IL-11 protein (His Tag)
Product Specifications
Background
Interleukin-11 (IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.
Abbreviation
IL-11
Synonyms
Interleukin; IL-11; Interleukin-11; Zcyto1; Zcyto10; Il11; AGIF; interleukin 11
UniProt
P47873
Accession Number
P47873
Expression System
E.coli
Tag
N-His
Sequence
Pro 22-Leu 199
Applications
Cell culture
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
50 2 x 106 IU/mg.6
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
20.0 kDa
Observed Molecular Weight
17-25 kDa
Species
Mouse
Available Sizes
Documents
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