Recombinant Mouse Neurotrophic Tyrosine Kinase Receptor Type 2/TrkB/NTRK2 (C-6His)
Product Specifications
Background
The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.
Abbreviation
TrkB; NTRK2
Synonyms
BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; NTRK2; Neurotrophic Tyrosine Kinase Receptor Type 2; TRKB; Trk-B; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B
UniProt
P15209
Accession Number
P15209
Expression System
HEK293 Cells
Tag
C-His
Sequence
Cys32-His429
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/h508l9
Product MSDS
https://789.bio/eb/CefTuL
Calculated Molecular Weight
45.3 kDa
Observed Molecular Weight
60-90 kDa
Species
Mouse
Available Sizes
Curated Selection
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