Recombinant Mouse CD27 Ligand/TNFSF7/CD70 (N-10His)
Product Specifications
Background
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Abbreviation
TNFSF7; CD70
Synonyms
CD27 ligand; CD27L; CD27LG; CD70; CD70 antigen; TNFSF7; Tumor necrosis factor ligand superfamily member 7
UniProt
Q05A52
Accession Number
Q05A52
Expression System
HEK293 Cells
Tag
N-His
Sequence
Gln47-Pro195
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/sxadx1
Product MSDS
https://789.bio/eb/5CeXr5
Calculated Molecular Weight
19.0 kDa
Observed Molecular Weight
25-30 kDa
Species
Mouse
Available Sizes
Curated Selection
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