Recombinant Mouse YM1/ECF-L/Chil3 Protein (Pro105Ser) (His Tag)

Product Specifications

Background

Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.

Abbreviation

YM1; ECF-L; Chil3

Synonyms

Chitinase-like protein; Chil; Chi3l; Chitinase-like protein 3; Chi3l3; Ym1; Chil3

UniProt

O35744

Accession Number

O35744

Expression System

HEK293 Cells

Tag

C-His

Sequence

Tyr22-Tyr398

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.