Recombinant Mouse NTPDase 2/ENTPD2 Protein (His Tag)
Product Specifications
Background
CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by preferentially converting ATP to ADP. CD39L1 plays a role in regulating thrombosis and inflammation which is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation. Alternative splicing of CD39L1 gene results in multiple transcript variants.
Abbreviation
NTPDase 2; ENTPD2
Synonyms
Ecto-Nucleoside Triphosphate Diphosphohydrolase 2; Ectonucleoside triphosphate diphosphohydrolase 2; Entpd2
UniProt
O55026
Accession Number
O55026
Expression System
HEK293 Cells
Tag
C-His
Sequence
Cys26-Ser462
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
49.2 kDa
Observed Molecular Weight
63-90 kDa
Formulation
2
Species
Mouse
Available Sizes
Curated Selection
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