Recombinant Mouse Galectin 9/LGALS9 Protein (GST Tag)
Product Specifications
Background
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin' s disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Abbreviation
Galectin 9; LGALS9
Synonyms
Gal-9; Galectin-9; Lgals9
UniProt
O08573
Accession Number
O08573-2
Expression System
E.coli
Tag
N-GST
Sequence
Met1-Thr322
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 85 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
62.8 kDa
Observed Molecular Weight
58 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 1mM EDTA, 5mM β-Mercaptoethanol, 5% Trehalose, 400mM NaCl, pH6.5.
Species
Mouse
Available Sizes
Documents
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