Recombinant Mouse IMPAD1/IMP3 Protein (His Tag)
Product Specifications
Background
IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an essential component of intracellular signaling pathways that mobilize calcium. Mouse IMPAD1 exhibits 91% sequence identity with the human homologue.
Abbreviation
IMPAD1; IMP3
Synonyms
IMPA3 ; Impad1; Inositol monophosphatase 3
UniProt
Q80V26
Accession Number
Q80V26
Expression System
HEK293 Cells
Tag
N-His
Sequence
Glu51-His356
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
34.3 kDa
Observed Molecular Weight
38 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Species
Mouse
Available Sizes
Curated Selection
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