Recombinant Mouse IL2Ra/CD25 Protein (His Tag)

Product Specifications

Background

The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc) . IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.

Abbreviation

IL2Ra; CD25

Synonyms

IDDM; alpha; CD25; CD25 antigen; IDDM10; IL-2 R alpha; IL-2 receptor subunit alpha; IL-2R subunit alpha; IL2-RA; IL-2-RA; interleukin 2 receptor; Interleukin-2 receptor subunit alpha; Ly-43; p55; TAC antigen; TCGFR; Il2r; Il2ra; Tac; p55; Ly-43; IL-2R&alpha

UniProt

P01590

Accession Number

P01590

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu22-Lys236

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.