Recombinant Mouse L-Selectin/SELL Protein (His Tag)

Product Specifications

Background

L-Selectin is a member of a family of Selectin that is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes and mediates a number of leukocyte-endothelial interactions, including the binding of lymphocytes to HEV of peripheral lymph node high endothelial venules (HEV), neutrophil rolling, and leukocyte attachment to cytokine-treated endothelium in vitro.

Abbreviation

L-Selectin; SELL

Synonyms

CD62 antigen-like family member L; CD62L; L-selectin; LECAM-1; LECAM1; Leukocyte adhesion molecule 1; Lnhr; Ly-22; Ly-m22; Lyam-1; Lyam1; Lymph node homing receptor; Lymphocyte antigen 22; Sell

UniProt

P18337

Accession Number

P18337

Expression System

HEK293 Cells

Tag

C-His

Sequence

Trp39-Asn332

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.