Recombinant Mouse MARCO Protein (His Tag)
Product Specifications
Background
MARCO (macrophage receptor with collagenous structure) is an 80 kDa type II transmembrane glycoprotein that belongs to the class Ascavenger receptor family. Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449 aa extracellulardomain (ECD) that includes a stalk region, a collagenlikeregion, and one SRCR domain. MARCO is constitutively expressed on the surface of splenic and lymph node macrophages. MARCO binds LPS, lipoteichoic acid, and otherdeterminants on Gram positive and Gram negative bacteria. It also binds modified LDL, CpG oligonucleotides, UGRP1, silica, and TiO2.
Abbreviation
MARCO
Synonyms
Ly112; Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Marco; Scara2
UniProt
Q60754
Accession Number
Q60754
Expression System
HEK293 Cells
Tag
N-His
Sequence
Gln70-Ser518
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/hdw9z1
Product MSDS
https://789.bio/eb/48OWP0
Calculated Molecular Weight
46.2 kDa
Observed Molecular Weight
55-65 kDa
Species
Mouse
Available Sizes
Curated Selection
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