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Recombinant Mouse Trefoil Factor 2/TFF2 Protein (His Tag)

Product Specifications

Background

Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma.

Abbreviation

Trefoil Factor 2; TFF2

Synonyms

SP; Sml1; Sp; Spasmolytic polypeptide; Tff2; Trefoil Factor 2

UniProt

Q03404

Accession Number

Q03404

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu24-Tyr129

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

12.7 kDa

Observed Molecular Weight

14 kDa

Species

Mouse

Available Sizes

Curated Selection

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