Recombinant Mouse VCAM1 Protein (Fc Tag)
Product Specifications
Background
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages) . IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.
Abbreviation
VCAM1
Synonyms
CD106; L1CAM; VCMA1; Vascular cell adhesion protein 1; Vcam-1; Vcam1
UniProt
P29533
Accession Number
P29533
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Phe25-Glu698
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/pp0gcc
Product MSDS
https://789.bio/eb/Ou14G8
Calculated Molecular Weight
101.4 kDa
Observed Molecular Weight
100-130 kDa
Species
Mouse
Available Sizes
Curated Selection
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