Recombinant Mouse CD73/NT5E Protein (His Tag)
Product Specifications
Background
Mouse CD73 is a glycosyl phosphatidylinositol (GPI) anchored membrane protein that belongs to the 5'-nucleotidase family. CD73 is an ecto 5'Nucleotidase expressed by most cell types. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 is a lymphocyte maturation marker that has functions independent of its catalytic activity. CD73 is also a regulator of leukocyte extravasation, a function that requires its 5'Nucleotidase activity.CD73 has also been reported to regulate expression of pro-inflammatory molecules in mouse endothelium.
Abbreviation
CD73; NT5E
Synonyms
5'-NT;5'-nucleotidase; AI447961; CD73; Ecto-5'-nucleotidase; NT; Nt5 Protein; eNT
Accession Number
Q61503
Expression System
HEK293 Cells
Tag
C-His
Sequence
Trp29-Phe550
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
58.8 kDa
Observed Molecular Weight
60 kDa
Formulation
2
Species
Mouse
Available Sizes
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