Recombinant Mouse Serpin F1/PEDF Protein
Product Specifications
Background
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.
Abbreviation
Serpin F1; PEDF
Synonyms
Caspin; Pedf; Pigment epithelium-derived factor; Sdf3; Serpin F1; Stromal cell-derived factor 3.
Accession Number
P97298
Expression System
E.coli
Tag
None
Sequence
Asp43-Thr417
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
42.0 kDa
Observed Molecular Weight
40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Species
Mouse
Available Sizes
Documents
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