Recombinant Mouse CNDP2/CPGL/PEPA Protein (His Tag)
Product Specifications
Background
Mouse cytosolic non-specific dipeptidase (CNDP2) is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 has 2 Isoform: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level) . Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 hydrolyzes a variety of dipeptides including L-carnosine and has a strong preference for Cys-Gly. It is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. It may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.
Abbreviation
CNDP2; CPGL; PEPA
Synonyms
CNDP dipeptidase 2; CNDP2; Cytosolic non-specific dipeptidase; Dip-2; Glutamate carboxypeptidase-like protein 1; Pep-1; Pep1
Accession Number
Q9D1A2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Asn475
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
53.8 kDa
Observed Molecular Weight
56-60 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
Species
Mouse
Available Sizes
Documents
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