Recombinant Mouse CD48 Protein (His Tag)
Product Specifications
Background
CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells (DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48 expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation.
Abbreviation
CD48
Synonyms
AI449234; AW610730; BCM1; BLAST-1; BLAST1; Bcm-1; CD48; MEM-102; SLAM Family Member 2; SLAMF2; Sgp-60
Accession Number
Q18PH8
Expression System
HEK293 Cells
Tag
C-His
Sequence
Phe23-Arg216
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/1h5p1k
Product MSDS
https://789.bio/eb/LGi5mT
Calculated Molecular Weight
23.1 kDa
Observed Molecular Weight
45-50 kDa
Species
Mouse
Available Sizes
Curated Selection
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