Recombinant Mouse DDR2 Kinase/CD167b Protein (His Tag)
Product Specifications
Background
Discoidin domain receptor-2 (DDR2) is a cell surface tyrosine kinase receptor that can be activated by soluble collagen and has been implicated in diverse physiological functions including organism growth and wound repair. DDR2 binds to and is activated by collagen I, II, III, V, and X, with the notable exception of basement membrane collagen IV. DDR2 is expressed in connective tissues arising from embryonic mesoderm. DDR2 regulates cell proliferation, cell adhesion, migration, and extracellular matrix remodeling.
Abbreviation
DDR2 Kinase; CD167b
Synonyms
CD167 antigen-like family member B; CD167b; Ddr2; Discoidin domain receptor 2; Discoidin domain-containing receptor 2; Neurotrophic tyrosine kinase; Ntrkr3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10; receptor-related 3; tyro10
UniProt
Q03146
Accession Number
Q62371
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln24-Arg399
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/rxuq50
Product MSDS
https://789.bio/eb/L0OCWD
Calculated Molecular Weight
43.5 kDa
Observed Molecular Weight
60-75 kDa
Species
Mouse
Available Sizes
Curated Selection
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