Recombinant Mouse DDR2 Kinase/CD167b Protein (His Tag)

Product Specifications

Background

Discoidin domain receptor-2 (DDR2) is a cell surface tyrosine kinase receptor that can be activated by soluble collagen and has been implicated in diverse physiological functions including organism growth and wound repair. DDR2 binds to and is activated by collagen I, II, III, V, and X, with the notable exception of basement membrane collagen IV. DDR2 is expressed in connective tissues arising from embryonic mesoderm. DDR2 regulates cell proliferation, cell adhesion, migration, and extracellular matrix remodeling.

Abbreviation

DDR2 Kinase; CD167b

Synonyms

CD167 antigen-like family member B; CD167b; Ddr2; Discoidin domain receptor 2; Discoidin domain-containing receptor 2; Neurotrophic tyrosine kinase; Ntrkr3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10; receptor-related 3; tyro10

UniProt

Q03146

Accession Number

Q62371

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln24-Arg399

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.