Recombinant Mouse α-Synuclein/SNCA Protein
Product Specifications
Background
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB) .
Abbreviation
Α-Synuclein; SNCA
Synonyms
Alpha-synuclein; NACP; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; Snca
UniProt
O55042
Accession Number
O55042
Expression System
E.coli
Tag
None
Sequence
Met1-Ala140
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.5 kDa
Observed Molecular Weight
17 kDa
Species
Mouse
Available Sizes
Documents
Frequently Asked Questions
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