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Recombinant Mouse VEGF-D/VEGFD Protein (His Tag)

Product Specifications

Background

Mouse vascular endothelial growth factor D, (VEGFD) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is a secreted protein and highly expressed in fetal and adult lung. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors. The structure and function of this protein is similar to VEGFC. VEGFD is growth factor which active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels.

Abbreviation

VEGF-D; VEGFD

Synonyms

FIGF; VEGFD; Vascular endothelial growth factor D; c-Fos-induced growth factor

UniProt

P97946

Accession Number

P97946

Expression System

HEK293 Cells

Tag

C-His

Sequence

Phe98-Ser206

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.1 kDa

Observed Molecular Weight

17-20 kDa

Species

Mouse

Available Sizes

Curated Selection

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