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Recombinant Mouse TGM2/Transglutaminase 2 Protein (His Tag)

Product Specifications

Background

Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme, It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

TGM2; Transglutaminase 2

Synonyms

Protein-glutamine gamma-glutamyltransferase 2; TGase-2; Tgm2; Tissue transglutaminase; Transglutaminase C

UniProt

P21981

Accession Number

P21981

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala2-Ala686

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

78.0 kDa

Observed Molecular Weight

70-90 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5.

Species

Mouse

Available Sizes

Frequently Asked Questions

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