Recombinant Mouse TGM2/Transglutaminase 2 Protein (His Tag)
Product Specifications
Background
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme, It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
TGM2; Transglutaminase 2
Synonyms
Protein-glutamine gamma-glutamyltransferase 2; TGase-2; Tgm2; Tissue transglutaminase; Transglutaminase C
UniProt
P21981
Accession Number
P21981
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala2-Ala686
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
78.0 kDa
Observed Molecular Weight
70-90 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5.
Species
Mouse
Available Sizes
Documents
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