Recombinant Mouse SerpinF2/SERPINF2 Protein (Fc Tag)
Product Specifications
Background
Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.
Abbreviation
SerpinF2; SERPINF2
Synonyms
Alpha-2-AP; Alpha-2-PI; Alpha-2-antiplasmin; Alpha-2-plasmin inhibitor; Serpin F2; Serpinf2
UniProt
Q61247
Accession Number
Q61247
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Val28-Lys491
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
79.3 kDa
Observed Molecular Weight
90-120 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0.
Species
Mouse
Available Sizes
Documents
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