Recombinant Mouse MMP12/MMP-12/HME Protein (His Tag)
Product Specifications
Background
Matrix metalloproteinase-12 (MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Abbreviation
MMP12; MMP-12; HME
Synonyms
MME; MMP-12; Macrophage metalloelastase; Matrix metalloproteinase-12; Mme; Mmel; Mmp12
UniProt
P34960
Accession Number
P34960
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala29-Cys473
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
53.0 kDa
Observed Molecular Weight
64 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl,0.01%Tween 80, 1mM EDTA, 50% Glycerol, pH6.0.
Species
Mouse
Available Sizes
Curated Selection
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