Recombinant Mouse LDHA/LDH1 Protein (His Tag)
Product Specifications
Background
Mouse Lactate dehydrogenase A (LDHA) is a member of the LDH/MDH superfamily and LDH family. LDHA catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria.
Abbreviation
LDHA; LDH1
Synonyms
L-lactate dehydrogenase; LDHA; Ldh1
UniProt
P06151
Accession Number
P06151
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Phe332
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
37.5 kDa
Observed Molecular Weight
37 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50%Glycerol, 500 mMNaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween 80, 1mM EDTA, pH9.0.
Species
Mouse
Available Sizes
Frequently Asked Questions
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