Recombinant Mouse IL-1A/IL-1α Protein
Product Specifications
Background
Mouse Interleukin-1 (IL-1) designates two proteins, IL-1α and IL-1β, which are the products of distinct genes, but recognize the same cell surface receptors. IL-1α and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.
Abbreviation
IL-1A; IL-1α
Synonyms
Hematopoietin; IL1F; Hematopoietin-1; IL1; IL1-A; IL1F1; IL-1α; Preinterleukin 1 Alpha; Pro-Interleukin-1-Alpha; Il-1a; Interleukin-1 alpha; IL-1 alpha; Il1a
UniProt
P01582
Accession Number
P01582
Expression System
E.coli
Tag
C-His
Sequence
Ser115-Ser270
Applications
Cell culture
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
50 2 x 108 IU/mg.8
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/qpvq1k
Product MSDS
https://789.bio/eb/LGWnvL
Calculated Molecular Weight
18.9 kDa
Observed Molecular Weight
20 kDa
Species
Mouse
Available Sizes
Curated Selection
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