Recombinant Mouse CD32b/FCGR2B Protein (His Tag)

Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.

CD32; Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII; Fcgr2; Fcgr2b; IgG Fc receptor II beta; Low affinity immunoglobulin gamma Fc region receptor II; Ly-17; Lymphocyte antigen 17

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.