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Recombinant Mouse Ephrin-B1/EFNB1 Protein (Fc & His Tag)

Product Specifications

Background

Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Ephrin-B1 is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.

Abbreviation

Ephrin-B1; EFNB1

Synonyms

EFL-3; EFL3; EFNB1; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; EPLG2; Ephrin-B1; LERK-2; LERK2

UniProt

P52795

Accession Number

P52795

Expression System

HEK293 Cells

Tag

C-Fc-His

Sequence

Lys30-Ser229

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

49.8 kDa

Observed Molecular Weight

58-80 kDa

Species

Mouse

Available Sizes

Curated Selection

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