Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (aa 17-420, His Tag)
Product Specifications
Background
Carboxypeptidase A4 (CPA4) is a member of the peptidase M14 family. CPA4 is metalloprotease that could be involved in the histone hyperacetylation pathway. CPA4 binds one zinc ion per subunit and could catalyze to release of a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val.They have distinct expression patterns and different specificities for example, preferentially cleaving aromatic (carboxypeptidase As) or basic (carboxypeptidase Bs) residues. Several, such as carboxypeptidase Xs, have lost their catalytic activity. Carboxypeptidases play important roles in digestion of food, processing of bioactive peptides and blood coagulation.
Abbreviation
Carbonic Anhydrase 4; CA4
Synonyms
CA-IV; CA4; CAIV; Car4; Carbonate dehydratase IV; EC4.2.1.1; RP17; carbonic anhydrase 4; carbonic anhydrase IVRP17; carbonic dehydratase IV; retinitis pigmentosa 17
UniProt
Q6P8K8
Accession Number
Q6P8K8
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gly17-Tyr420
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
46.7 kDa
Observed Molecular Weight
50 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
Species
Mouse
Available Sizes
Documents
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