Recombinant Mouse CD48 Protein (His Tag)
Product Specifications
Background
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
Synonyms
AI449234; AW610730; BCM1; BLAST-1; BLAST1; Bcm-1; CD48; MEM-102; SLAM Family Member 2; SLAMF2; Sgp-60
UniProt
P18181
Accession Number
NP_031675.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Arg 216
Applications
ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 85 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to bind human 2B4 and biotinylated recombinant mouse CD2 in functional ELISA.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
23.7 kDa
Species
Mouse
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