Recombinant Mouse LAMP2/CD107b Protein (His Tag)
Product Specifications
Background
LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2) . LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.
Synonyms
CD107b; LGP-B; Lamp-2; Lamp-2a; Lamp-2b; Lamp-2c; LampII; Mac3
UniProt
P17047
Accession Number
P17047-1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu 26-Asn 379
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 97 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/1cxd8o
Product MSDS
https://789.bio/eb/9G0COK
Calculated Molecular Weight
40.6 kDa
Observed Molecular Weight
70-80 kDa
Species
Mouse
Curated Selection
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