Recombinant Mouse FCRL1 Protein (aa 1-204, His Tag)
Product Specifications
Background
Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains threeIg-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level) . Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.
Synonyms
BXMAS1-like protein 1; Bxmas1; Bxmh1; Bxmh1b; CD307a; Fc receptor homolog 1; Fc receptor-like protein 1; FcR-like protein 1; FcRH1; FcRL1; Fcrh1; Fcrh1l; Fcrh1s; IFGP family protein 1; Ifgp1 Protein; mBXMH1; mIFGP1; moFcRH1
UniProt
Q8R4Y0
Accession Number
Q8R4Y0-2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Thr204
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/d5h1hd
Product MSDS
https://789.bio/eb/a9uDG4
Calculated Molecular Weight
21.6 kDa
Species
Mouse
Curated Selection
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