Recombinant Mouse EphA3 Protein (Fc Tag)
Product Specifications
Background
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
Synonyms
AW492086; Cek4; ETK1; End3; Hek; Hek4; Mek4; Tyro4
UniProt
Q8BRB1
Accession Number
NP_034270.1
Expression System
HEK293 Cells
Tag
C-hFc
Sequence
Met1-His541
Applications
ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized mouse EFNA5-His at 10 μg/ml (100 μl/well) can bind mouse EPHA3-Fc, The EC50 of rat mouse EPHA3-Fc is 12.3-28.9 ng/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/gdaui9
Product MSDS
https://789.bio/eb/jDaPaH
Calculated Molecular Weight
85.7 kDa
Observed Molecular Weight
96 kDa
Species
Mouse
Curated Selection
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