Triclabendazole
Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME) -dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica[1][2][3].
Product Specifications
CAS Number
68786-66-3
Product Name Alternative
CGA89317
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bcl-2 Family; Caspase; Parasite; PARP; Pyroptosis
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/triclabendazole.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CSC1=NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N1
Molecular Formula
C14H9Cl3N2OS
Molecular Weight
359.66
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Bax; Bcl-2; Caspase 3; Caspase 8; Caspase 9; Leishmania; PARP
Available Sizes
Frequently Asked Questions
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