Recombinant Human MMP7 protein (N-His)
Product Specifications
Background
Matrix metalloproteinase-7 proenzyme (proMMP-7) is a 30.47 kDa matrix metalloproteinases with 273 amino acid residues. MMP-7 restricted production by normal mucosal and exocrine gland epithelial cells, as well as by carcinoma cells. Functionally, it involved breakdown of extracellular matrix (casein, gelatins of types I, III, IV, and V, and fibronectin) in normal physiological processes and disease processes. MMP-7 is contributed to early tumor development during carcinogenesis. proMMP7 activation by trypsin occurs via an intermediate cleaved at Lys50-Asn51.
Abbreviation
MMP7
Synonyms
MMP-7; MPSL1; PUMP-1
UniProt
P09237
Accession Number
P09237
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Lys 267
Field of Research
Cardiovascular, Signal Transduction, Cancer, Cell Biology
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/hzqeah
Product MSDS
https://789.bio/eb/X9yL04
Calculated Molecular Weight
30.5 kDa
Observed Molecular Weight
26 kDa
Species
Human
Available Sizes
Curated Selection
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