Recombinant Human FGF-23 protein (His Tag)

Product Specifications

Background

Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Up-regulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Abbreviation

FGF-23

Synonyms

FGFN

UniProt

Q9GZV9

Accession Number

Q9GZV9

Expression System

E.coli

Tag

C-His

Sequence

Tyr 25-Ile 251

Applications

Cell culture

Field of Research

Signal Transduction, Stem Cells, Cancer, Developmental Biology

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.