Recombinant Human FGF-23 protein (His Tag)
Product Specifications
Background
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Up-regulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
Abbreviation
FGF-23
Synonyms
FGFN
UniProt
Q9GZV9
Accession Number
Q9GZV9
Expression System
E.coli
Tag
C-His
Sequence
Tyr 25-Ile 251
Applications
Cell culture
Field of Research
Signal Transduction, Stem Cells, Cancer, Developmental Biology
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
50
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.3 kDa
Observed Molecular Weight
26 kDa
Species
Human
Available Sizes
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