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Human Tau-441 (K18, P301L) Protein, Tag Free (HPLC verified)

Selected Variant

GTR19028860-01

Size: 100 µg

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Product Specifications

UniProt

P10636

Expression Region

Gln 244 - Glu 372

Reactivity

Human

Conjugation

Unconjugated

Tag

Native

Source

Human Tau-441 (K18, P301L) Protein, Tag Free (orb1675333) is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L) ) .

Field of Research

Neuroscience

Endotoxin

0.01 EU per μg

Purity

95%

Form

Liquid

Molecular Weight

13.8 kDa

Storage Conditions

-70°C

Notes

For research use only.

Applications Notes

This protein carries no "tag". The protein has a calculated MW of 13.8 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE) .

NCBI Accession Number

P301, P10636

Preservative

50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH7.5

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