Recombinant Human BMP-11 protein (His Tag)
Product Specifications
Background
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Abbreviation
BMP-11
Synonyms
GDF-11; Growth/Differentiation Factor-11
UniProt
O95390
Accession Number
O95390
Expression System
E.coli
Tag
C-His
Sequence
Asn 299-Ser 407
Applications
Cell culture
Field of Research
Signal Transduction, Cell Biology, Neuroscience
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
5050 for this effect is
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
13.4 kDa
Observed Molecular Weight
16 kDa
Species
Human
Available Sizes
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