Recombinant Human FasL protein (His Tag)

Product Specifications

Background

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Abbreviation

FasL

Synonyms

APT1LG1; APTL; Apo I Ligand; CD178; CD95L; TNFSF6; soluble Fas Ligand (sFasL)

UniProt

P48023

Accession Number

P48023

Expression System

E.coli

Tag

N-His-SUMO

Sequence

Gln 130-Leu 281

Applications

Cell culture

Field of Research

Cell Biology, Immunology, Stem Cells

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50 1 x 106 IU/mg.6

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.