Recombinant Human AITRL protein (His Tag)
Product Specifications
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Abbreviation
AITRL
Synonyms
GITRL; TL6; TNFSF18; TNLG2A; hGITRL
UniProt
Q9UNG2
Accession Number
Q9UNG2
Expression System
E.coli
Tag
C-His
Sequence
Gln 50-Ile 176 (L170I, F175E)
Applications
Cell culture
Field of Research
Immunology, Tags & Cell Markers, Signal Transduction, Cancer, Cardiovascular
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
Measure by its ability to induce IL-8 secretion in human PBMC using a concentration range of 5-200 ng /mL. Note: Result may vary from different PBMC donors.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.3 kDa
Observed Molecular Weight
11 kDa
Species
Human
Available Sizes
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