Recombinant Human IL-29 protein (His Tag)

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

IFN-lambda; Interleukin; ytokine Zcyto; Cytokine Zcyto; IFNL; ZCYTO; IFN-λ; lambda; Cytokine Zcyto21; IFN-lambda-1; IFN-λ1; IL-29; interferon; interferon lambda 1; Interferon lambda-1; Interleukin-29; lambda 1; ytokine Zcyto21; IL29; ZCYTO21; IFNL1

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.