Recombinant Human IL-16 (129 a.a.) protein (N-His)
Product Specifications
Background
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
Abbreviation
IL-16
Synonyms
NIL; Interleukin; IL16; LCF; NIL16; PRIL16; prIL-16; IL-16; Interleukin-16; LCF (Lymphocyte Chemoattractant Factor) ; Lymphocyte chemoattractant factor; Pro-Interleukin-16
UniProt
Q14005
Accession Number
Q14005
Expression System
E.coli
Tag
C-His
Sequence
Met 1203-Ser 1332
Field of Research
Immunology
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/pt9gc0
Product MSDS
https://789.bio/eb/eHmvDS
Calculated Molecular Weight
14.1 kDa
Observed Molecular Weight
18 kDa
Species
Human
Available Sizes
Curated Selection
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